Selection and the origin of species
نویسندگان
چکیده
Do we know anything about its regulation? A little. In animal cells, components of the class I phosphatidylinositol (PI) 3-kinase pathway including Akt and Tor act as inhibitors, whereas the lipid phosphatase PTEN, class III PI 3-kinase and p70 S6 kinase appear to be positive regulators. In yeast, Tor kinase and protein kinase A are inhibitory, while PI 3kinase is required for autophagy. Many questions remain regarding the networked interactions that control autophagic responses to different stimuli.
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عنوان ژورنال:
- Current Biology
دوره 15 شماره
صفحات -
تاریخ انتشار 2005